Esquina is a borough of San Serena, located in the north east suburbs of the city. Esquina is a mainly residential borough, with many green spaces. The borough is also amongst the wealthiest in the city, with many of the San Serena's most expensive residential areas located in the borough.

Barrios of San Luis
Aravaca - Carcelén - Cuerabaca - El Centro - Esquina - Neuquén - Pasadiso - Puerto Guillerme
Puerto Sassari - San Lorenzo - San Rafael - Villa Elisa - Villa García - Villa Mateo

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